Can albuterol be blamed for lactic acidosis?

Atrial fibrillation in an asthmatic patient with albuterol-induced lactic acidosis.

Asthma is a highly prevalent chronic respiratory disease affecting millions of people worldwide. Short-acting beta 2-agonists induce bronchodilation and usually are prescribed as a rescue medication. They are recognized as a cause of hyperlactatemia and, less frequently, lactic acidosis. Short-acting beta 2-agonists are also known for their potentially adverse cardiovascular effects, such as at...

Transient lactic acidosis as a side effect of inhaled salbutamol.

Too much testing?

In their recent article in CHEST (January 2014) on the treatment of acute asthma with albuterol, Lewis et al 1 show that high levels of lactate during such treatment are highly prevalent; in addition, high plasma albuterol concentration is signifi cantly correlated with hyperlactatemia. In a previous case involving a woman with asthma, we described lactic acidosis (pH 7.29) and a high level of ...

Effect of vitamin D3 and guanidinoacetic acid on performance, some physiological parameters, carcass characteristics and behavior of broilers affected by lactic acidosis

Extended Abstract Introduction and objectives: Lactic acidosis occurs as a result of hypoxia and rapid growth of broilers and can be considered as a physiological stress. In two experiments, the effect of extra nutritional levels of vitamin D3 and guanidinoacetic acid was investigated on performance, relative weight of organs, some physiological and behavioral parameters of broiler chicks unde...

Metformin-Associated Lactic Acidosis in a Patient With Normal Renal Function

We report a case of metformin-associated lactic acidosis (MALA) in the setting of normal renal function and review the relevant medical literature. A 77-year-old female diagnosed with type 2 diabetes mellitus previously treated with insulin and gliclazide MR was started on metformin. A few weeks later, she was found to have lactic acidosis. Renal function was normal, and no severe underlying il...